房燕，女，理学博士，教授，研究生导师，1983年2月生，山东郓城人

研究方向

海洋生物与环境的相互作用、海洋牧场资源养护效果评估、资源增殖。

学习经历

博士：2007.9-2010.7捕鱼游戏海洋研究所海洋生态学专业

硕士：2004.9-2007.7中国海洋大学海洋生物学专业

本科：2000.9-2004.7山东农业大学生物技术专业

工作经历

2024.7-今 乐乐捕鱼

2015.1-2024.7鲁东大学农乐乐捕鱼

2010.8-2014.12山东省海洋资源与环境研究院渔业资源研究中心

科研项目

[1]2023.11-2026.12国家重点研发计划“黄渤海生态智慧型海洋牧场构建与融合发展模式（2023YFD2401104）”子任务，智能化监测装备，主持；

[2] 2021.01-2024.12国家自然科学基金面上项目“环境孕激素对四角蛤蜊的生殖毒性效应及机制（42076137）”，主持；

[3] 2019.11-2022.12国家重点研发计划“蓝色粮仓科技创新”专项“黄渤海现代化海洋牧场构建与立体开发模式示范（2019YFD0902102）”子任务资源养护效果评估技术示范，主持；

[4] 2019.11-2022.12国家重点研发计划“蓝色粮仓科技创新”专项“滩涂增养殖技术与生态农牧化新模式（2019YFD0900700）”子任务滩涂贝类新品种（品系）的选择（选育）及本地化苗种繁育，主持；

[5] 2019.1-2021.12烟台市重点研发计划“基于生物标志物的海洋牧场生态环境评价技术构建与示范（2019XDHZ097）”，主持；

[6] 2013.1-2015.12 国家自然科学基金青年项目“四角蛤蜊对典型PBDEs胁迫的分子响应机制(41206120)” ，主持；

[7] 2011.1-2013.12 烟台市科技发展项目“基于生物标志物的莱州湾污染综合评价技术研究(2011062)”，主持。

代表性论文

[1]Fang Y, Liu B, Wang J, et al. Norgestrel shows androgenic properties and triggers reproductive neuroendocrine toxicity in the testes of Pacific oysters (Crassostrea gigas)[J]. Journal of Hazardous Materials, 2025: 138467.

[2]Zheng, T., Zhong, H.Y., Chen, C.K., Xu, D.Z., Zhang, Y.L., Xu, J.C., Li, D., Fang, Y. and Yang, C.Y. Norgestrel drives mitochondrial collapse and plasma membrane impairment in Pacific oyster (Crassostrea gigas) sperm by triggering premature acrosome reaction. Comparative Biochemistry and Physiology D-Genomics & Proteomics, 2026, 101952 (60).

[3]Xiangfei Li,Yanyan Yang,Hua Xu,Jia Wang,Zhixu Chen,Baojun Liu,Linlin Fan,Yan Fang*,Fan Li*.Norgestrel causes oxidative damage to the digestive gland of the clam Mactra veneriformis.Aquaculture Reports,2024,37:102250.

[4]Mingzhu Li,Zhixu Chen,Ming Li,Jiugang Zhang,Bingqing Xu,Yanyan Yang,Xiangfei Li,Linlin Fan,Baojun Liu,Tao Zheng,Yan Fang*and Fan Li*.Integrated assessment of trace elements in a marine ranching area based on multi-species and multi-level biomarkers:a case study in China’s national-level marine ranching demonstration area.Frontiers in marine science,2024,6:1413847.

[5]Xiaoran Zhao,Qing Wang,Xiangfei Li,Hua Xu,Chuanbo Ren,Yanyan Yang,Shuhao Xu,Guoxing Wei,Yujun Duan,Zhitao Tan,Yan Fang*.Norgestrel causes digestive gland injury in the clam Mactra veneriformis:An integrated histological,transcriptomics,and metabolomics study.Science of the total environment,2023,871:162110.

[6]Shuhao Xu,Weijun Wang,Bingqing Xu,Xin He,Zhixu Chen,Xiaoran Zhao,Yifei Zhang,Shuyu Zhou,Yan Fang*,Qing Wang*.In vitro exposure to environmentally relevant concentrations of norgestrel affects sperm physiology and reproductive success of the Pacific oyster Crassostrea gigas.Marine Environmental Research,2023,186:105938.

[7]Maosheng Liu Hua Xu,Qiang Zou,Fei Fang,Shan Sun,Yuting Zhao,Xin He,Yonghui Bo,Lei Yao,Yan Fang*.Assessment of heavy metal pollution in Laizhou Bay(China)using the ecological risk index and the integrated biomarker response of the goby Acanthogobius ommaturus.Journal of Oceanology and Limnology,2023,41:1519-1536.

[8]Yan Fang,Xiyun Yang,Shujuan Zhang,Xuyang Chen,Gang Lin,Yuqing Zhang,Mengjiao Wang,Mingzhu Li.Transcriptome study on immune response against Vibrio parahaemolyticus challenge in gill of abalone Haliotis discus hannai Ino.Frontiers in marine science,2022,9:956317.

[9]Zhu Na,Yang Yanyan,Xu Hua,Wang Qing,Wei Yanyan,Li Mingzhu,Li Fan,Wang Yiqi,Zhang Huawei,Liu Yihao,Wang Xiaoming,Fang Yan*.Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis.Environmental Toxicology and Pharmacology,2019,68:19-26.

[10]Dong Shihang,Yang Yanyan,Cheng Bo,Ren Chuanbo,Zhang Huawei,Xu Hua,Zhu Na,Wang Wansheng,Dang Yongjian,Li Mingzhu,Chen Jun,Wang Kai,Zhang Libin,Fang Yan*.Responses of antioxidant defenses in the clam Mactra veneriformis to 2,2′,4,4′tetrabromodiphenyl ether exposure.Comparative Biochemistry Physiology Part C:Toxicology&Pharmacology,2019,217:98-105.

[11]Shi Pengju,Dong Shihang,Zhang Huanjun,Wang Peiliang,Niu Zhuang,Fang Yan*.Transcriptome profiling analysis of Mactra veneriformis by deep sequencing after exposure to 2,2′,4,4′-tetrabromodiphenyl ether.Journal of Oceanology and Limnology,2018,36(2):490-507.

[12]Yan Fang,Hongsheng Yang,Baozhong Liu,Libin Zhang.Transcriptional response of lysozyme,metallothionein,and superoxide dismutase to combined exposure to heavy metals and bacteria in Mactra veneriformis.Comparative Biochemistry and Physiology-Part C:Toxicology&Pharmacology,2013,157:54-62.

[13]Yan Fang,Hongsheng Yang,Baozhong Liu.Tissue-specific response of metallothionein and superoxide dismutase in the clam Mactra veneriformis under sublethal mercury exposure.Ecotoxicology(IF=3.29),2012,21:1593-1602.

[14]Yan Fang,Hongsheng Yang,Tianming Wang,Baozhong Liu,Heling Zhao,Muyan Chen.Metallothionein and superoxide dismutase responses to sublethal cadmium exposure in the clam Mactra veneriformis.Comparative Biochemistry and Physiology-Part C:Toxicology&Pharmacology(IF=2.96),2010,151,325-333.

[15]Yan Fang,Zhenbo Lv,Huanjun Zhang,Fan Li,Bingqing Xu.Seasonal Variation of Nutrients and Environmental Impact Factors in Sanggou Bay.Applied Mechanics and Materials,2012,137:328-334.

[16]Fang Yan,Wang Yuhong,Liu Yihao,Xu Hua,Lv Zhenbo.Feature of phytoplankton community and canonical correlation analysis with environmental factors in Xiaoqing River estuary in autumn.Procedia Engineering,2012,37:19-24.

[17]房燕,吕振波,张焕君,李凡,徐炳庆.荣成湾营养盐分布和变化特征.海洋湖沼通报,2012,3:81-89.

[18]房燕,杨红生.镉和汞两种重金属离子对四角蛤蜊血细胞DNA损伤的初步研究.海洋科学，2011,35(2):1-5.

[19]房燕,汝少国,邴欣,姜明．久效磷对金鱼精巢超显微结构和特征性酶活性的影响．水产学报，2007,31,568-574.

[20]房燕参编.海洋牧场知识科普问答，中国农业出版社，2023.

[21]房燕参编.增殖型海洋牧场技术模式，中国农业出版社，2021.

[22]房燕参编.海洋牧场概论，科学出版社，2020.

[23]房燕参编.海岸带生态农牧场创新发展战略研究，科学出版社，2020.

[24]房燕参编.海洋牧场构建原理与实践，科学出版社，2017.

[25]房燕参编.胶州湾资源与环境，海洋出版社，2012.

发明专利

[1]房燕，刘宝珺，范琳琳，郑涛，张云岭，王娟，仲浩洋.海水水体水质检测装置及方法，ZL 202510313977.7，2025，已授权.

[2]房燕,刘宝珺,范琳琳,郑涛,张云岭,王娟,仲浩洋.海水水体水质检测装置及方法.发明专利, ZL 2025103139777, 2025,已授权.

[3]房燕,徐华,孙超,黄经献,徐栋,陈峙旭,黎香飞.一种海洋生物保护用海水治理装置.发明专利,ZL 2023 1 0113038.9, 2023,已授权.

[4]房燕,梁欢,柳茂生,王一奇,姚蕾,邹强,王维忠,付建革,柯可.利用四角蛤蜊DMRT基因检测海洋中PBDEs的方法.发明专利, ZL2019110415920,2020,已转化.

荣誉奖励

[1]第一届水产类高校青年教师教学技能大赛特等奖,2019.

[2]山东省第七届高校青年教师教学比赛二等奖,2020.

[3]全国研究生“渔菁英”挑战赛优秀奖指导教师,2019, 2023.

参与发布的标准

[1]近海产卵场生境适宜性评价技术指南,山东省地方标准, DB37/T 4938—2025.

[2]游泳动物产卵场、索饵场、越冬场和洄游通道健康评价技术规范,山东省地方标准, DB37/T 4746—2024.

[3]钝吻黄盖鲽苗种培育技术规程,山东省地方标准,DB37/T 2296—2013.

联系方式

通讯地址：山东省烟台市乐乐捕鱼北19-411

电子邮箱：[email protected]